Comment
doi: 10.1016/j.immuni.2007.08.003.
CD8(+) T cell differentiation: choosing a path through T-bet
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- PMID: 17723210
- DOI: 10.1016/j.immuni.2007.08.003
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Comment
CD8(+) T cell differentiation: choosing a path through T-bet
Immunity.
2007 Aug.
Free article
Abstract
Activated CD8(+) T cells can differentiate into transient effector cells or long-lived memory cells. In this issue of Immunity, Joshi et al. (2007) suggest that inflammatory cytokines dictate this balance by regulating the expression of the transcription factor T-bet.
Comment on
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Inflammation directs memory precursor and short-lived effector CD8(+) T cell fates via the graded expression of T-bet transcription factor.Immunity. 2007 Aug;27(2):281-95. doi: 10.1016/j.immuni.2007.07.010. Immunity. 2007. PMID: 17723218 Free PMC article.
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