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. 1991 Jun;29(5-6):271-4.
doi: 10.1007/BF00590107.

Genetic deficiency of complement component C8 in the rabbit: evidence of a translational defect in expression of the alpha-gamma subunit

M Komatsu  1 , K Yamamoto, H Mikami, J M Sodetz
Affiliations

Genetic deficiency of complement component C8 in the rabbit: evidence of a translational defect in expression of the alpha-gamma subunit

M Komatsu et al. Biochem Genet. 1991 Jun.

Abstract

We examined the molecular basis for rabbit C8 alpha-gamma deficiency (C8D) using human C8 cDNA probes. Sequential probing of normal rabbit poly(A)+RNA revealed messages of 2.1, 1.9, and 0.8 kb for alpha, beta, and gamma, respectively. Corresponding analysis of C8D rabbit poly(A)+RNA identified messages for alpha and gamma of the same size and amounts as normal rabbits. Thus, C8 alpha-gamma deficiency in the rabbit appears to be the result of a translational rather than a transcriptional defect.

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References

    1. Biochemistry. 1987 Jun 16;26(12):3565-70 - PubMed
    1. J Clin Invest. 1990 Sep;86(3):884-8 - PubMed
    1. Biochemistry. 1987 Jun 16;26(12):3556-64 - PubMed
    1. Biochem Biophys Res Commun. 1987 Nov 30;149(1):282-8 - PubMed
    1. FASEB J. 1987 Sep;1(3):209-14 - PubMed

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