Resolved: capillary endothelium is a major contributor to the glomerular filtration barrier
- PMID: 17724232
- DOI: 10.1681/ASN.2007060687
Resolved: capillary endothelium is a major contributor to the glomerular filtration barrier
Abstract
There is growing debate as to the primal role of capillary endothelial cells in the barrier function of the glomerular filter. Two experts argue the points for and against. Clearly unresolved is agreement whether glomerular capillary endothelium has fenestrae subtended by diaphragms.
Similar articles
-
Glomerular endothelium: a porous sieve and formidable barrier.Exp Cell Res. 2012 May 15;318(9):964-72. doi: 10.1016/j.yexcr.2012.02.032. Epub 2012 Mar 21. Exp Cell Res. 2012. PMID: 22465480 Review.
-
Glomerular permeability: a never-ending saga.Am J Physiol Renal Physiol. 2009 Jun;296(6):F1266-8. doi: 10.1152/ajprenal.00152.2009. Epub 2009 Mar 25. Am J Physiol Renal Physiol. 2009. PMID: 19321597 No abstract available.
-
What determines glomerular capillary permeability?J Clin Invest. 2004 Nov;114(10):1412-4. doi: 10.1172/JCI23577. J Clin Invest. 2004. PMID: 15545991 Free PMC article.
-
Structural determinants of glomerular hydraulic permeability.Am J Physiol. 1994 Jan;266(1 Pt 2):F1-12. doi: 10.1152/ajprenal.1994.266.1.F1. Am J Physiol. 1994. PMID: 8304474
-
Endothelial glycocalyx dysfunction in disease: albuminuria and increased microvascular permeability.J Pathol. 2012 Mar;226(4):562-74. doi: 10.1002/path.3964. J Pathol. 2012. PMID: 22102407 Review.
Cited by
-
High-normal albuminuria is associated with subclinical atherosclerosis in male population with estimated glomerular filtration rate ≥60 mL/min/1.73 m2: A cross-sectional study.PLoS One. 2019 Aug 1;14(8):e0218290. doi: 10.1371/journal.pone.0218290. eCollection 2019. PLoS One. 2019. PMID: 31369578 Free PMC article.
-
Therapeutic targets in focal and segmental glomerulosclerosis.Curr Opin Nephrol Hypertens. 2008 Jul;17(4):386-92. doi: 10.1097/MNH.0b013e32830464f4. Curr Opin Nephrol Hypertens. 2008. PMID: 18660675 Free PMC article. Review.
-
Lactate dehydrogenase is associated with flow-mediated dilation in hypertensive patients.Sci Rep. 2023 Jan 14;13(1):768. doi: 10.1038/s41598-023-27614-3. Sci Rep. 2023. PMID: 36641500 Free PMC article.
-
Reduction in basal nitric oxide activity causes albuminuria.Diabetes. 2011 Feb;60(2):572-6. doi: 10.2337/db09-1630. Diabetes. 2011. PMID: 21270268 Free PMC article. Clinical Trial.
-
Brain-endocrine interactions: a microvascular route in the mediobasal hypothalamus.Endocrinology. 2009 Dec;150(12):5509-19. doi: 10.1210/en.2009-0584. Epub 2009 Oct 16. Endocrinology. 2009. PMID: 19837874 Free PMC article.
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources