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Review
. 2007 Aug;17(4):474-80.
doi: 10.1016/j.sbi.2007.07.004. Epub 2007 Aug 28.

Protein engineering with bacterial display

Affiliations
Review

Protein engineering with bacterial display

Patrick S Daugherty. Curr Opin Struct Biol. 2007 Aug.

Abstract

Recent improvements in bacterial surface display systems coupled with efficient selection and screening strategies are propelling bacterial display systems to the forefront of peptide and protein engineering. The ability to analyze and screen very large protein libraries using cell-sorting instrumentation coupled with the ease of manipulating bacteria provides new capabilities for the protein engineering toolbox.

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