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. 2007 Sep 21;5(18):2884-90.
doi: 10.1039/b708507a. Epub 2007 Aug 3.

Beta-amino acid-containing hybrid peptides--new opportunities in peptidomimetics

Marie-Isabel Aguilar  1 , Anthony W Purcell, Romila Devi, Rebecca Lew, Jamie Rossjohn, A Ian Smith, Patrick Perlmutter
Affiliations

Beta-amino acid-containing hybrid peptides--new opportunities in peptidomimetics

Marie-Isabel Aguilar et al. Org Biomol Chem. .

Abstract

Hybrid peptides consisting of alpha-amino acids with judiciously placed beta-amino acids show great promise as peptidomimetics in an increasing range of therapeutic applications. This reflects a combination of increased stability, high specificity and relative ease of synthesis.

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