Lack of glucose phosphotransferase function in phosphofructokinase mutants of Escherichia coli
- PMID: 177406
- PMCID: PMC233222
- DOI: 10.1128/jb.126.2.852-860.1976
Lack of glucose phosphotransferase function in phosphofructokinase mutants of Escherichia coli
Abstract
Phosphofructokinase (pfkA) mutants of Escherichia coli are impaired in growth on all carbon sources entering glycolysis at or above the level of fructose 6-phosphate (nonpermissive carbon sources), but growth is particularly slow on sugars, such as glucose, which are normally transported and phosphorylated by the phosphoenolpyruvate, (PEP)-dependent phosphotransferase system (PTS).
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