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Case Reports
. 1991 Nov;67(793):1018-20.
doi: 10.1136/pgmj.67.793.1018.

Polymyositis complicating D-penicillamine treatment

A O Aydintug  1 , R Cervera, D D'Cruz, G Ramírez, R A Asherson, M A Khamashta, G R Hughes
Affiliations
Case Reports

Polymyositis complicating D-penicillamine treatment

A O Aydintug et al. Postgrad Med J. 1991 Nov.

Abstract

Although there is good evidence that D-penicillamine can induce polymyositis, the exact pathogenic mechanism remains unclear. We report two patients with psoriatic arthritis and primary biliary cirrhosis respectively, who developed polymyositis while receiving D-penicillamine treatment for their primary diseases. Whether D-penicillamine treatment was the sole cause of polymyositis or acted as a trigger for the development of a secondary autoimmune disease is discussed.

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References

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