doi: 10.1055/s-2006-960116.
T-cadinol: a pharmacologically active constituent of scented myrrh: introductory pharmacological characterization and high field 1H- and 13C-NMR data
Affiliations
- PMID: 1775577
- DOI: 10.1055/s-2006-960116
Item in Clipboard
T-cadinol: a pharmacologically active constituent of scented myrrh: introductory pharmacological characterization and high field 1H- and 13C-NMR data
Planta Med.
1991 Aug.
Abstract
Fractionation of an ethyl acetate extract of scented myrrh (resin of Commiphora guidottii Chiov., Burseraceae), using the guinea pig ileum test to monitor pharmacological activity, resulted in isolation of the sesquiterpene (+)-T-cadinol. High field NMR spectroscopy yielded new detailed 1H- and 13C-NMR data for the compound. T-cadinol was shown to have a concentration-dependent smooth muscle relaxing effect on the isolated guinea pig ileum and a dose-dependent inhibitory effect on cholera toxin-induced intestinal hypersecretion in mice.
Similar articles
-
Minor components with smooth muscle relaxing properties from scented myrrh (Commiphora guidotti).Planta Med. 1997 Jun;63(3):251-4. doi: 10.1055/s-2006-957665. Planta Med. 1997. PMID: 9225607
-
Spasmolytic and antidiarrhoeal properties of the Yucatec Mayan medicinal plant Casimiroa tetrameria.J Pharm Pharmacol. 2005 Sep;57(9):1081-5. doi: 10.1211/jpp.57.9.0002. J Pharm Pharmacol. 2005. PMID: 16105228
-
Inhibitory effect of extract of Ipomoea pes-caprae on guinea-pig ileal smooth muscle.Acta Pharm Nord. 1989;1(1):41-4. Acta Pharm Nord. 1989. PMID: 2597337
-
Spasmolytic effects, mode of action, and structure-activity relationships of stilbenoids from Nidema boothii.J Nat Prod. 2004 Feb;67(2):160-7. doi: 10.1021/np030303h. J Nat Prod. 2004. PMID: 14987052
-
Chemical constituents of Artemisia arborescens and the effect of the aqueous extract on rat isolated smooth muscle.Planta Med. 1995 Jun;61(3):242-5. doi: 10.1055/s-2006-958064. Planta Med. 1995. PMID: 7617767
Cited by
-
Seeing the Unseen of the Combination of Two Natural Resins, Frankincense and Myrrh: Changes in Chemical Constituents and Pharmacological Activities.Molecules. 2019 Aug 24;24(17):3076. doi: 10.3390/molecules24173076. Molecules. 2019. PMID: 31450584 Free PMC article. Review.
-
Recent Advances in Multiple Strategies for the Biosynthesis of Sesquiterpenols.Biomolecules. 2025 May 3;15(5):664. doi: 10.3390/biom15050664. Biomolecules. 2025. PMID: 40427558 Free PMC article. Review.
-
Calcium channels at the adrenergic neuroeffector junction in the rabbit ear artery.Naunyn Schmiedebergs Arch Pharmacol. 1993 Jun;347(6):617-23. doi: 10.1007/BF00166944. Naunyn Schmiedebergs Arch Pharmacol. 1993. PMID: 8395661
-
(E)-2,6,10-Trimethyldodec-8-en-2-ol: An Undescribed Sesquiterpenoid from Copaiba Oil.Molecules. 2021 Jul 23;26(15):4456. doi: 10.3390/molecules26154456. Molecules. 2021. PMID: 34361609 Free PMC article.
-
Chemical Composition and In Vitro Antioxidant Activity of Salvia aratocensis (Lamiaceae) Essential Oils and Extracts.Molecules. 2023 May 12;28(10):4062. doi: 10.3390/molecules28104062. Molecules. 2023. PMID: 37241803 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
