Creating next-generation microscopists: structural and molecular biology at the crossroads
- PMID: 17760837
- PMCID: PMC3823254
- DOI: 10.1111/j.1582-4934.2007.00072.x
Creating next-generation microscopists: structural and molecular biology at the crossroads
Abstract
This paper highlights the importance of advanced microscopy and microanalysis in the pursuit of quality research in the biological and life sciences. With the growing complexity of modern microscopes, there is substantial risk of incorrect use or misinterpretation of data by the inexperienced researcher. This paper emphasizes the need for collaboration between biological microscopists and molecular biologists, within the context of centralized facilities and supported by first-class training, to fully realize the power of these unique instruments in modern biology and to create the next generation of molecular microscopists.
References
-
- Tsien RY. Imagining imaging's future. Nat Rev Mol Cell Biol. 2003;(Suppl):S16–S21. - PubMed
-
- Giepmans BN, Adams SR, Ellisman MH, Tsien RY. The fluorescent toolbox for assessing protein location and function. Science. 2006;312:217–24. - PubMed
-
- Swanson JA, Peters PJ. Subcellular imaging technologies – microscopic visual thinking. Curr Opin Microbiol. 2005;8:313–5.
-
- Lucic V, Forster F, Baumeister W. Structural studies by electron tomography: from cells to molecules. Ann Rev Biochem. 2005;74:833–65. - PubMed
-
- Griffiths G. Bringing electron microscopy back into focus for cell biology. Trends Cell Biol. 2001;11:153–4. - PubMed
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