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Review
. 2007 Aug 30:7:167.
doi: 10.1186/1471-2407-7-167.

Radiotherapeutic alternatives for previously irradiated recurrent gliomas

Stephanie E Combs  1 , Jürgen Debus, Daniela Schulz-Ertner
Affiliations
Review

Radiotherapeutic alternatives for previously irradiated recurrent gliomas

Stephanie E Combs et al. BMC Cancer. .

Abstract

Re-irradiation for recurrent gliomas has been discussed controversially in the past. This was mainly due to only marginal palliation while being associated with a high risk for side effects using conventional radiotherapy. With modern high-precision radiotherapy re-irradiation has become a more wide-spread, effective and well-tolerated treatment option. Besides external beam radiotherapy, a number of invasive and/or intraoperative radiation techniques have been evaluated in patients with recurrent gliomas. The present article is a review on the available methods in radiation oncology and summarizes results with respect to outcome and side effects in comparison to clinical results after neurosurgical resection or different chemotherapeutic approaches.

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Figures

Figure 1
Figure 1
Severe treatment-related toxicity in patients with recurrent gliomas treated with FSRT, SRS of hypofractionated RT.
See this image and copyright information in PMC

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