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Review
. 1991 Nov;16(11):417-22.
doi: 10.1016/0968-0004(91)90167-t.

Diversity and specificity in transcriptional regulation: the benefits of heterotypic dimerization

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Review

Diversity and specificity in transcriptional regulation: the benefits of heterotypic dimerization

P Lamb et al. Trends Biochem Sci. 1991 Nov.

Abstract

Many eukaryotic transcription factors contain domains that mediate the formation of homo- and heterodimers. The widespread occurrence of such domains suggests that they are important to the genetic regulatory apparatus. In this review we explore the contributions that heterotypic dimerization may make to the generation of regulatory diversity.

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