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Comment
. 2007 Sep;13(3):322-4.
doi: 10.1016/j.devcel.2007.08.006.

Coping with stress: ATF6alpha takes the stage

Ekaterina Bobrovnikova-Marjon  1 , J Alan Diehl
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Coping with stress: ATF6alpha takes the stage

Ekaterina Bobrovnikova-Marjon et al. Dev Cell. 2007 Sep.
Free article

Abstract

In this issue of Developmental Cell, two groups, Yamamoto et al. and Wu et al., describe the generation of mice with targeted deletion of the ATF6alpha gene. While ATF6alpha is nonessential for embryonic and postnatal development, deletion has a profound effect on the transcriptional program elicited by endoplasmic reticulum stress, revealing a broader than anticipated role for ATF6 in this signaling network.

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