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. 1970 May 15;168(3933):849-50.
doi: 10.1126/science.168.3933.849.

L-dopa: effect on concentrations of dopamine, norepinephrine, and serotonin in brains of mice

G M Everett, J W Borcherding

L-dopa: effect on concentrations of dopamine, norepinephrine, and serotonin in brains of mice

G M Everett et al. Science. .

Abstract

Large doses of L-dopa given to mice produced marked increases in brain dopamine, no change in norepinephrine, and a remarkable decrease in brain serotonin. This reduction apparently results from a release or displacement, or both, of serotonin from its storage sites.

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