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doi: 10.1016/j.neuron.2007.08.014.
Does epileptiform activity contribute to cognitive impairment in Alzheimer's disease?
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- PMID: 17785172
- DOI: 10.1016/j.neuron.2007.08.014
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Does epileptiform activity contribute to cognitive impairment in Alzheimer's disease?
Neuron.
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Abstract
Alzheimer's disease is a devastating neurological disorder. The role of hyperexcitability in the disease's cognitive decline is not completely understood. In this issue of Neuron, Palop et al. report both limbic seizures and presumed homeostatic responses to seizures in an animal model of Alzheimer's.
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Aberrant excitatory neuronal activity and compensatory remodeling of inhibitory hippocampal circuits in mouse models of Alzheimer's disease.Neuron. 2007 Sep 6;55(5):697-711. doi: 10.1016/j.neuron.2007.07.025. Neuron. 2007. PMID: 17785178 Free PMC article.
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