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. 1991;41(5):330-9.
doi: 10.1159/000154021.

The C5 isozyme of serum cholinesterase and adult weight

E A Chautard-Freire-Maia  1 , S L Primo-Parmo, G Picheth, M A Lourenço, M M Vieira
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The C5 isozyme of serum cholinesterase and adult weight

E A Chautard-Freire-Maia et al. Hum Hered. 1991.

Abstract

The relationship between the CHE2 locus of serum cholinesterase (BChE) and adult human weight was studied in a sample of 225 CHE2 C5+ individuals and 225 CHE2 C5- controls matched for sex, height, age and race. With respect to the intensity of the C5 band staining (scored 1-6), 113 individuals had faint C5 bands (scores 1-3) and 112 intense C5 bands (scores 4-6). The individuals with intense CHE2 C5+ phenotype showed a significantly lower mean adult weight (64.66 +/- 0.73 kg) when compared to their controls (70.59 +/- 0.97 kg) and a significant reduction in weight variance (59.81 and 105.18, respectively). Individuals with faint C5 bands, although showing a negative correlation between weight and C5 band intensity, did not differ from their controls in mean weight.

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