Glioblastoma: looking at the currently marketed sigma-1 agonists and antagonists
- PMID: 17786188
- PMCID: PMC1950439
- DOI: 10.1593/neo.07451
Glioblastoma: looking at the currently marketed sigma-1 agonists and antagonists
Comment on
-
4-IBP, a sigma1 receptor agonist, decreases the migration of human cancer cells, including glioblastoma cells, in vitro and sensitizes them in vitro and in vivo to cytotoxic insults of proapoptotic and proautophagic drugs.Neoplasia. 2007 May;9(5):358-69. doi: 10.1593/neo.07130. Neoplasia. 2007. PMID: 17534441 Free PMC article.
References
-
- Megalizzi V, Mathieu V, Mijatovic T, Gailly P, Debeir O, De Neve N, Van Damme M, Bontempi G, Haibe-Kains B, Decaestecker C, et al. 4-IBP, a sigma1 receptor agonist, decreases the migration of human cancer cells, including glioblastoma cells, in vitro and sensitizes them in vitro and in vivo to cytotoxic insults of proapoptotic and proautophagic drugs. Neoplasia. 2007;9(5):358–369. - PMC - PubMed
-
- Hashimoto K, Fujita Y, Iyo M. Phencyclidine-induced cognitive deficits in mice are improved by subsequent subchronic administration of fluvoxamine: role of sigma-1 receptors. Neuropsychopharmacology. 2007;32(3):514–521. - PubMed
-
- Stahl SM. Antidepressant treatment of psychotic major depression: potential role of the sigma receptor. CNS Spectr. 2005;10(4):319–323. - PubMed
-
- Maurice T, Meunier J, Feng B, Ieni J, Monaghan DT. Interaction with sigma(1) protein, but not N-methyl-D-aspartate receptor, is involved in the pharmacological activity of donepezil. J Pharmacol Exp Ther. 2006;317(2):606–614. - PubMed
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources