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. 1944 Aug 4;100(2588):108-10.
doi: 10.1126/science.100.2588.108.

A METHOD OF OBTAINING RENAL VENOUS BLOOD IN UNANESTHETIZED PERSONS WITH OBSERVATIONS ON THE EXTRACTION OF OXYGEN AND SODIUM PARA-AMINOHIPPURATE

J V Warren, E S Brannon, A J Merrill

A METHOD OF OBTAINING RENAL VENOUS BLOOD IN UNANESTHETIZED PERSONS WITH OBSERVATIONS ON THE EXTRACTION OF OXYGEN AND SODIUM PARA-AMINOHIPPURATE

J V Warren et al. Science. .

Abstract

Catheterization of the renal vein offers a safe and relatively simple method of obtaining blood as it leaves the kidney in the resting unanesthetized human subject. In preliminary observation on 8 subjects the renal arteriovenous oxygen difference varied from 1.9 to 2.8 volumes per cent., averaging 2.3 volumes per cent. Sodium para-amino hippurate, at low plasma levels, was 88 per cent. extracted during a single circulation through the kidney.

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