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. 1981 Jul 31;213(4507):549-51.
doi: 10.1126/science.213.4507.549.

Nullisomic tetrahymena: eliminating germinal chromosomes

P J Bruns, T E Brussard

Nullisomic tetrahymena: eliminating germinal chromosomes

P J Bruns et al. Science. .

Abstract

Germinal and somatic functions in Tetrahymena are performed separately by the micro- and macronuclei, respectively. Cells with haploid micronuclei were mated with diploids to yield monosomic progeny. These were induced to undergo a form of self-fertilization, generating cells lacking both copies of one or more of the five chromosomes in the micronucleus while still possessing a complete macronuclear genome.

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