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Review
. 1991 Mar;16(3):215-26.
doi: 10.1007/BF00966084.

The structural and functional heterogeneity of glutamic acid decarboxylase: a review

M G Erlander  1 , A J Tobin
Affiliations
Review

The structural and functional heterogeneity of glutamic acid decarboxylase: a review

M G Erlander et al. Neurochem Res. 1991 Mar.

Abstract

Studies of the GABA-synthetic enzyme glutamate decarboxylase (glutamic acid decarboxylase; GAD; E.C.4.1.1.15) began in 1951 with the work of Roberts and his colleagues. Since then, many investigators have demonstrated the structural and functional heterogeneity of brain GAD. At least part of this heterogeneity derives from the existence of two GAD genes.

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