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Review
. 2007 Jul;33(7):773-81.
doi: 10.1016/j.joen.2007.01.002. Epub 2007 Feb 23.

Update on the adaptive immune responses of the dental pulp

Chin-Lo Hahn  1 , Frederick R Liewehr
Affiliations
Review

Update on the adaptive immune responses of the dental pulp

Chin-Lo Hahn et al. J Endod. 2007 Jul.

Abstract

Recent advances in immunology have disclosed the enormous complexity of the immune regulatory system. The dental pulp is equipped to mount adaptive immune responses to caries, which include at least antigen-presenting cells, lymphocytes, mast cells and their cytokines, and chemokines. The purpose of this review is to summarize our current understanding of the roles of these cellular and molecular components in the irreversibly inflamed pulp. The immunopathology of abscess formation and the mechanisms for painless pulpitis are also discussed.

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