A solitary fibrofolliculoma in the eyelid

Abstract

Purpose: To report the first case of a solitary eyelid fibrofolliculoma and to review the literature.

Methods: A 37-year-old female patient visited the outpatient department with a lesion in the right upper lid that had been growing steadily for a year. The patient had visited the local clinic, and under the diagnosis of chalazion had received incision and curettage twice, but the lesion had recurred.

Results: The 5x5 mm lesion was located near the upper lid margin. It was a red, hemispheric, smooth nodule, relatively solid to palpation and not painful. Excision and biopsy were performed, and through a histological exam, the diagnosis of fibrofolliculoma was later confirmed.

Conclusions: Solitary fibrofolliculoma is rare, and to the authors' knowledge, a lesion arising in the eyelid has not yet been reported. Fibrofolliculoma should be included in the differential diagnosis when a localized mass lesion arising in the eyelid is encountered.

Fig. 1

(A) Preoperative appearance shows a solitary, firm, non-tender, well-demarcated and skin-colored bean-sized mass on the right upper eyelid. (B) Postoperative (11 months) appearance shows the right upper lid, which has maintained its shape; the lesion has not yet recurred.

Fig. 2

Low-power histopathologic appearance of a fibrofolliculoma showing proliferation of fibrotic stroma surrounding the central dilated infundibulum of the hair follicle with proliferative thin epithelial strands (Hematoxylin-eosin stain ×40).

Fig. 3

High-power histopathologic photograph showing the characteristic appearances of proliferating infundibular epithelial strands with perifollicular fibrous reaction, anastomosing to form an epithelial network (arrow: hair follicle, Hematoxylin-eosin stain, ×100).