doi: 10.1016/0035-9203(91)90347-2.
Genetic diversity of Plasmodium falciparum in a village in eastern Sudan. 1. Diversity of enzymes, 2D-PAGE proteins and antigens
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- PMID: 1780978
- DOI: 10.1016/0035-9203(91)90347-2
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Genetic diversity of Plasmodium falciparum in a village in eastern Sudan. 1. Diversity of enzymes, 2D-PAGE proteins and antigens
Trans R Soc Trop Med Hyg.
1991 Sep-Oct.
Erratum in
- Trans R Soc Trop Med Hyg 1991 Nov-Dec;85(6):713
Abstract
Twenty-nine plasmodium falciparum isolates from patients in Asar village, eastern Sudan, were characterized for variation in 18 different genetically controlled characters, including iso-enzymes, proteins detected by two-dimensional polyacrylamide gel electrophoresis and blood-stage antigens. Considerable allelic diversity in the genes determining these characters was detected. Each isolate contained genetically distinct parasites. Fifteen individuals were infected with more than one parasite genotype. The diversity of parasite types is most probably generated by recombination during mosquito transmission of mixed parasite clones.
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