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. 1968 Sep 13;161(3846):1158-60.
doi: 10.1126/science.161.3846.1158.

Ecdysones and analogs: effects on development and reproduction of insects

W E Robbins, J N Kaplanis, M J Thompson, T J Shortino, C F Cohen, S C Joyner

Ecdysones and analogs: effects on development and reproduction of insects

W E Robbins et al. Science. .

Abstract

Ingestion of certain synthetic ecdysone analogs inhibited larval growth and development in several species of insects, whereas 20-hydroxyecdysone was inactive or considerably less active. Natural 20-hydroxyecdysone and ponasterone A, and a synthetic ecdysone analog inhibited ovarian maturation and egg production in the adult housefly. These effects appeared to be related to hormonal activity.

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