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. 1963 Apr 26;140(3565):405.
doi: 10.1126/science.140.3565.405.

Plaque Formation in Agar by Single Antibody-Producing Cells

N K Jerne, A A Nordin

Plaque Formation in Agar by Single Antibody-Producing Cells

N K Jerne et al. Science. .

Abstract

Distinct plaques, each of which is due to the release of hemolysin by a single antibody-forming cell, are revealed by complement after incubation, in an agar layer, of a mixture of sheep red cells and lymphoid cells from a rabbit immunized with sheep red cells.

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