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Review
. 2007 Sep 22;370(9592):1089-100.
doi: 10.1016/S0140-6736(07)61305-1.

The cardiovascular toll of stress

Daniel J Brotman  1 , Sherita H Golden, Ilan S Wittstein
Affiliations
Review

The cardiovascular toll of stress

Daniel J Brotman et al. Lancet. .

Erratum in

  • Lancet. 2007 Dec 1;370(9602):1828

Abstract

Psychological stress elicits measurable changes in sympathetic-parasympathetic balance and the tone of the hypothalamic-pituitary-adrenal axis, which might negatively affect the cardiovascular system both acutely-by precipitating myocardial infarction, left-ventricular dysfunction, or dysrhythmia; and chronically-by accelerating the atherosclerotic process. We provide an overview of the association between stress and cardiovascular morbidity, discuss the mechanisms for this association, and address possible therapeutic implications.

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