Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1991 Dec;20(6):471-4.
doi: 10.1007/BF00334774.

Chemical mutagenesis and DNA synthesis in cdc8, a DNA replication mutant of Saccharomyces cerevisiae

H Baranowska  1 , J Zuk
Affiliations

Chemical mutagenesis and DNA synthesis in cdc8, a DNA replication mutant of Saccharomyces cerevisiae

H Baranowska et al. Curr Genet. 1991 Dec.

Abstract

Incubation of cdc8 mutants of the yeast Saccharomyces cerevisiae in YPD under permissive conditions, when DNA replication is taking place, prior to transfer to restrictive conditions, strongly stimulates induction of cdc+ colonies of ethyl methane sulphonate (EMS)- and methyl methane sulphonate (MMS)-treated yeast strains HB23 (cdc8-1/cdc8-3), HB26 (cdc8-3/cdc8-3) and HB7 (cdc8-1/cdc8-1). After diepoxybutane (DEB) treatment, both the induction of cdc+ colonies and their stimulation after incubation in YPD under permissive conditions is low. The results obtained show that stimulation of induction of cdc+ colonies under permissive conditions occurs not only after UV-treatment, but also after treatment with such mutagens as EMS and MMS.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

References

    1. Mutat Res. 1988 Jul-Aug;200(1-2):133-47 - PubMed
    1. Proc Natl Acad Sci U S A. 1984 Sep;81(18):5821-5 - PubMed
    1. Can J Biochem. 1982 Mar;60(3):172-84 - PubMed
    1. Environ Mutagen. 1982;4(6):695-725 - PubMed
    1. Annu Rev Biochem. 1982;51:655-93 - PubMed

Publication types

MeSH terms

LinkOut - more resources