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. 2007 Sep;71(9):2329-32.
doi: 10.1271/bbb.70264. Epub 2007 Sep 7.

Dillapiol and Apiol as specific inhibitors of the biosynthesis of aflatoxin G1 in Aspergillus parasiticus

Mehdi Razzaghi-Abyaneh  1 , Tomoya Yoshinari, Masoomeh Shams-Ghahfarokhi, Mohammad-Bagher Rezaee, Hiromichi Nagasawa, Shohei Sakuda
Affiliations
Free article

Dillapiol and Apiol as specific inhibitors of the biosynthesis of aflatoxin G1 in Aspergillus parasiticus

Mehdi Razzaghi-Abyaneh et al. Biosci Biotechnol Biochem. 2007 Sep.
Free article

Abstract

Dillapiol was isolated from the essential oil of dill as a specific inhibitor of aflatoxin G1 production. It inhibited aflatoxin G1 production by Aspergillus parasiticus with an IC50 value of 0.15 microM without inhibiting aflatoxin B1 production or fungal growth. Apiol and myristicin, congeners of dillapiol, showed similar activity with IC50 values of 0.24 and 3.5 microM, respectively.

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