Schizophrenia drug says goodbye to dopamine
- PMID: 17828217
- DOI: 10.1038/nm0907-1018
Schizophrenia drug says goodbye to dopamine
Comment in
-
Glutamate agonists for schizophrenia stimulate dopamine D2High receptors.Schizophr Res. 2008 Feb;99(1-3):373-4. doi: 10.1016/j.schres.2007.11.007. Schizophr Res. 2008. PMID: 18077139 No abstract available.
Comment on
-
Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: a randomized Phase 2 clinical trial.Nat Med. 2007 Sep;13(9):1102-7. doi: 10.1038/nm1632. Epub 2007 Sep 2. Nat Med. 2007. PMID: 17767166 Clinical Trial.
Similar articles
-
Schizophrenia therapy: beyond atypical antipsychotics.Nat Rev Drug Discov. 2008 Jun;7(6):471-2. doi: 10.1038/nrd2571. Epub 2008 May 16. Nat Rev Drug Discov. 2008. PMID: 18483482 No abstract available.
-
Positive allosteric modulators of the metabotropic glutamate receptor 2 for the treatment of schizophrenia.Expert Opin Ther Pat. 2009 Sep;19(9):1259-75. doi: 10.1517/13543770903045009. Expert Opin Ther Pat. 2009. PMID: 19552508 Review.
-
Dopamine and its relation to schizophrenia and antipsychotic drugs.Bull Menninger Clin. 1978 Jul;42(4):321-38. Bull Menninger Clin. 1978. PMID: 29683 No abstract available.
-
Metabotropic glutamate receptors as targets for novel antipsychotic treatments.Curr Pharm Biotechnol. 2012 Jun;13(8):1522-34. doi: 10.2174/138920112800784817. Curr Pharm Biotechnol. 2012. PMID: 22283756 Review.
-
Receptor pair for schizophrenia.Pediatr Res. 2008 Jul;64(1):1. doi: 10.1203/PDR.0b013e318180052a. Pediatr Res. 2008. PMID: 18574404 Free PMC article. No abstract available.
Cited by
-
Perspectives on the mGluR2/3 agonists as a therapeutic target for schizophrenia: Still promising or a dead end?Prog Neuropsychopharmacol Biol Psychiatry. 2015 Jul 3;60:66-76. doi: 10.1016/j.pnpbp.2015.02.012. Epub 2015 Feb 24. Prog Neuropsychopharmacol Biol Psychiatry. 2015. PMID: 25724760 Free PMC article. Review.
-
[Progress in locating the genetic causes of schizophrenia].Nervenarzt. 2009 Jan;80(1):6, 8, 10-1. doi: 10.1007/s00115-008-2614-z. Nervenarzt. 2009. PMID: 19132332 Review. German.
-
Preclinical evaluation of the antipsychotic potential of the mGlu2-positive allosteric modulator JNJ-40411813.Pharmacol Res Perspect. 2015 Mar;3(2):e00097. doi: 10.1002/prp2.97. Epub 2015 Jan 30. Pharmacol Res Perspect. 2015. PMID: 25692027 Free PMC article.
-
Reversal of cognitive deficits by an ampakine (CX516) and sertindole in two animal models of schizophrenia--sub-chronic and early postnatal PCP treatment in attentional set-shifting.Psychopharmacology (Berl). 2009 Nov;206(4):631-40. doi: 10.1007/s00213-009-1540-5. Epub 2009 Apr 24. Psychopharmacology (Berl). 2009. PMID: 19390843
-
Pharmacogenetics in psychiatry: are we ready for widespread clinical use?Schizophr Bull. 2008 Nov;34(6):1130-44. doi: 10.1093/schbul/sbn114. Epub 2008 Aug 27. Schizophr Bull. 2008. PMID: 18753306 Free PMC article. Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical