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Review
. 2007:59 Suppl 1:25-7.
doi: 10.4081/reumatismo.2007.1s.25.

Genetics of psoriasis and psoriatic arthritis

A Mathieu  1 , A Cauli, A Vacca, A Mameli, G Passiu, G Porru, M Piga, V Ibba, V Mura, S Sanna
Affiliations
Free article
Review

Genetics of psoriasis and psoriatic arthritis

A Mathieu et al. Reumatismo. 2007.
Free article

Abstract

Psoriasis and psoriatic arthritis are linked diseases characterised by (distinct ?) immune-mediated pathogenetic mechanisms and by a genetic background interacting with environmental factors. Some candidate susceptibility genes have been studied extensively; they include HLA genes, genes within the HLA region and genes outside the HLA region; among them corneodesmosin and other genes of PSORS1 region, MICA and TNF-a polymorphisms. The main findings in the literature are discussed.

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