Genetics of psoriasis and psoriatic arthritis
- PMID: 17828355
- DOI: 10.4081/reumatismo.2007.1s.25
Genetics of psoriasis and psoriatic arthritis
Abstract
Psoriasis and psoriatic arthritis are linked diseases characterised by (distinct ?) immune-mediated pathogenetic mechanisms and by a genetic background interacting with environmental factors. Some candidate susceptibility genes have been studied extensively; they include HLA genes, genes within the HLA region and genes outside the HLA region; among them corneodesmosin and other genes of PSORS1 region, MICA and TNF-a polymorphisms. The main findings in the literature are discussed.
Similar articles
-
The MICA-A9 triplet repeat polymorphism in the transmembrane region confers additional susceptibility to the development of psoriatic arthritis and is independent of the association of Cw*0602 in psoriasis.Arthritis Rheum. 1999 May;42(5):1010-6. doi: 10.1002/1529-0131(199905)42:5<1010::AID-ANR21>3.0.CO;2-H. Arthritis Rheum. 1999. PMID: 10323458
-
Tumor necrosis factor promoter polymorphism TNF*-857 is a risk allele for psoriatic arthritis independent of the PSORS1 locus.Arthritis Rheum. 2011 Dec;63(12):3801-6. doi: 10.1002/art.30591. Arthritis Rheum. 2011. PMID: 22127698
-
Polymorphism in MICA rather than HLA-B/C genes is associated with psoriatic arthritis in the Jewish population.Hum Immunol. 2001 Jun;62(6):632-8. doi: 10.1016/s0198-8859(01)00242-7. Hum Immunol. 2001. PMID: 11390038
-
What have we learned about genetic susceptibility in psoriasis and psoriatic arthritis?Curr Opin Rheumatol. 2015 Jan;27(1):91-8. doi: 10.1097/BOR.0000000000000136. Curr Opin Rheumatol. 2015. PMID: 25415529 Review.
-
Associations between the major histocompatibility complex class I chain-related gene A transmembrane (MICA-TM) polymorphism and susceptibility to psoriasis and psoriatic arthritis: a meta-analysis.Rheumatol Int. 2014 Jan;34(1):117-23. doi: 10.1007/s00296-013-2849-2. Epub 2013 Aug 22. Rheumatol Int. 2014. PMID: 23974432 Review.
Cited by
-
Unlocking relief: formulation, characterization, and in vivo assessment of salicylic acid-loaded microemulgel for psoriasis management.Naunyn Schmiedebergs Arch Pharmacol. 2025 Mar;398(3):3037-3047. doi: 10.1007/s00210-024-03447-3. Epub 2024 Sep 26. Naunyn Schmiedebergs Arch Pharmacol. 2025. PMID: 39325151
-
Genome-wide association study and admixture mapping identify different asthma-associated loci in Latinos: the Genes-environments & Admixture in Latino Americans study.J Allergy Clin Immunol. 2014 Aug;134(2):295-305. doi: 10.1016/j.jaci.2013.08.055. Epub 2014 Jan 7. J Allergy Clin Immunol. 2014. PMID: 24406073 Free PMC article.
-
Clinical features and types of articular involvement in patients with psoriatic arthritis.Clin Rheumatol. 2015 Jun;34(6):1091-6. doi: 10.1007/s10067-014-2746-4. Epub 2014 Jul 29. Clin Rheumatol. 2015. PMID: 25066919
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
Research Materials