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. 1973 Mar 30;179(4080):1324-6.
doi: 10.1126/science.179.4080.1324.

Toxin from Fusarium moniliforme: Effects on Plants and Animals

R J Cole, J W Kirksey, H G Cutler, B L Doupnik, J C Peckham

Toxin from Fusarium moniliforme: Effects on Plants and Animals

R J Cole et al. Science. .

Abstract

A mycotoxin-producing strain of Fusarium moniliforme was isolated from southern leaf blight-damaged corn seed. A water-soluble toxin, subsequently purified from the fungus, had an oral median lethal dose of 4.0 milligrams per kilogram in 1-day-old cockerels. The toxin also produced plant growth-regulating and phytotoxic effects on plant systems. Physical and chemical data presented for the toxin suggest a structurally new toxin. The trivial name "moniliformin" has been assigned to the toxin.

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