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. 1963 Jul 19;141(3577):266-7.
doi: 10.1126/science.141.3577.266.

Genetic Control of Differential Heat Tolerance in Two Strains of the Nematode Caenorhabditis elegans

H V Fatt, E C Dougherty

Genetic Control of Differential Heat Tolerance in Two Strains of the Nematode Caenorhabditis elegans

H V Fatt et al. Science. .

Abstract

Two strains (Bergerac and Bristol) of the nematode Caenorhabditis elegans, with different temperature tolerances, were reared axenically at 23 degrees to 25 degrees C. The Bergerac strain is heat sensitive (that is, it is sterile at maturity), whereas the Bristol strain is heat resistant (that is, it matures and reproduces normally). Hybrid hermaphrodites (F(1)), produced by crossing Bristol males and Bergerac hermaphrodites, are heat tolerant. Heat sensitivity segregates as a simple Mendelian recessive in the F(2) and F(3) generations.

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