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Case Reports
. 1991 Dec;47(3):337-339.
doi: 10.1016/0304-3959(91)90225-M.

Hyperalgesia and myoclonus with intrathecal infusion of high-dose morphine

Franco de Conno  1 , Augusto Caraceni, Cinzia Martini, Elio Spoldi, Monica Salvetti, Vittorio Ventafridda
Affiliations
Case Reports

Hyperalgesia and myoclonus with intrathecal infusion of high-dose morphine

Franco de Conno et al. Pain. 1991 Dec.

Abstract

We report the case of a patient who developed myoclonus and hyperalgesia following administration of high-dose subarachnoid morphine. This complication occurred with 40-80 mg/day continuous infusion. The pathophysiology of these side effects is discussed.

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