Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2007;69(2 Suppl):S56-8.
doi: 10.1016/j.ijrobp.2007.04.081.

Identifying and targeting hypoxia in head and neck cancer: a brief overview of current approaches

Affiliations

Identifying and targeting hypoxia in head and neck cancer: a brief overview of current approaches

Quynh-Thu Le. Int J Radiat Oncol Biol Phys. 2007.
No abstract available

PubMed Disclaimer

Figures

Figure 1
Figure 1
Cancer-specific survival by hypoxia marker score comprised of Galectin-1, Ephrin A1, Lysyl Oxidase, CA IX cytoplasmic and CA IX membrane staining, where a score of 1 was assigned to strong staining for each marker and a score of 0 to negative and week stainin. This has been adjusted for age and hemoglobin levels, 2 other significant factors on univariate analysis.
Figure 2
Figure 2
Replication of outcome data using the previously defined OPN value of 450 ng/ml in 86 new patients: Overall survival by OPN.

Similar articles

Cited by

References

    1. Nordsmark M, Bentzen SM, Rudat V, et al. Prognostic value of tumor oxygenation in 397 head and neck tumors after primary radiation therapy. An international multi-center study. Radiother Oncol. 2005;77:18–24. - PubMed
    1. Wendling P, Manz R, Thews G, et al. Heterogeneous oxygenation of rectal carcinomas in humans: a critical parameter for preoperative irradiation? Adv Exp Med Biol. 1984;180:293–300. - PubMed
    1. Raleigh JA, Calkins-Adams DP, Rinker LH, et al. Hypoxia and vascular endothelial growth factor expression in human squamous cell carcinomas using pimonidazole as a hypoxia marker. Cancer Res. 1998;58:3765–3768. - PubMed
    1. Evans SM, Hahn S, Pook DR, et al. Detection of hypoxia in human squamous cell carcinoma by EF5 binding. Cancer Res. 2000;60:2018–2024. - PubMed
    1. Kaanders JH, Wijffels KI, Marres HA, et al. Pimonidazole binding and tumor vascularity predict for treatment outcome in head and neck cancer. Cancer Res. 2002;62:7066–7074. - PubMed

Publication types

MeSH terms