Wilms' tumour in adults: a case report and review of the literature

Abstract

Background: Wilms' tumour is a very rare adult malignancy representing 1% of adult renal tumours. It is however the most common renal tumour of childhood, and adult patients are treated in accordance with paediatric protocols.

Aim: To review modern day management of adult Wilms' tumour.

Methods: We report a case of adult Wilms' tumour and discuss the management including the use of newer treatment modalities.

Results: Following diagnostic nephrectomy, our patient was treated with chemotherapy in accordance with North American paediatric protocols and PET scanning was used to diagnose early relapse.

Conclusion: In the absence of randomised controlled data, central reporting of cases of adult Wilms' Tumour may help improve management. The incorporation of newer chemotherapeutic agents, high-dose therapy and PET scanning into treatment protocols should improve outcome for these patients.