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. 2007 Sep;70(9):1529-31.
doi: 10.1021/np070259w. Epub 2007 Sep 14.

Brunneins A-C, beta-carboline alkaloids from Cortinarius brunneus

Axel Teichert  1 , Jürgen Schmidt, Andrea Porzel, Norbert Arnold, Ludger Wessjohann
Affiliations

Brunneins A-C, beta-carboline alkaloids from Cortinarius brunneus

Axel Teichert et al. J Nat Prod. 2007 Sep.

Abstract

Four beta-carboline alkaloids, brunneins A-C (1-3) and 3-(7-hydroxy-9H-beta-carboline-1-yl)propanoic acid (4), were isolated from fruiting bodies of the agaricoid fungus Cortinarius brunneus. The structures of 1-3 were determined by analysis of NMR and MS data, and the structure of compound 4 was determined by comparison with published data. Brunnein A (1) exhibited very low cholinesterase inhibitory effects and no cytotoxicity.

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