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Case Reports
. 1991 Winter;13(4):459-64.
doi: 10.1097/00043426-199124000-00011.

Intrathoracic carcinoma in an 11-year-old girl showing a translocation t(15;19)

U R Kees  1 , M T Mulcahy, M L Willoughby
Affiliations
Case Reports

Intrathoracic carcinoma in an 11-year-old girl showing a translocation t(15;19)

U R Kees et al. Am J Pediatr Hematol Oncol. 1991 Winter.

Abstract

We report here a rare case of intrathoracic undifferentiated carcinoma in an 11-year-old girl. The biopsy tissue stained with antibodies against cytokeratin and carcino-embryonic antigen. The same staining was obtained using a cell line, PER-403, which was derived from the tumor. DNA from PER-403 cells was tested for the presence of Epstein-Barr virus genes, yielding a negative result. The cytogenetic analysis found a translocation t(15;19) (p12;q13), which has not previously been described in a carcinoma.

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