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Review
. 2007 Aug;27(3):529-49.
doi: 10.1016/j.iac.2007.07.008.

Evaluation and differential diagnosis of marked, persistent eosinophilia

Thomas B Nutman  1
Affiliations
Review

Evaluation and differential diagnosis of marked, persistent eosinophilia

Thomas B Nutman. Immunol Allergy Clin North Am. 2007 Aug.

Abstract

Hypereosinophilic syndromes (HES) are a group of heterogeneous disorders many of which remain ill-defined. By definition, the HES must be distinguished from other disorders with persistently elevated eosinophilia with a defined cause. Although marked eosinophilia worldwide is most commonly caused by helminth (worm) infections, the diagnostic approach must include noninfectious (nonparasitic) causes of marked eosinophilia as well.

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