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Case Reports
. 2008 Feb;65(2):279-80.
doi: 10.1111/j.1365-2125.2007.03020.x. Epub 2007 Sep 13.

Serious haematological toxicity of cyclophosphamide in relation to CYP2B6, GSTA1 and GSTP1 polymorphisms

Agnès Tran, François Bournerias, Christine Le Beller, Olivier Mir, Elisabeth Rey, Gérard Pons, Michel Delahousse, Jean-Marc Tréluyer
Case Reports

Serious haematological toxicity of cyclophosphamide in relation to CYP2B6, GSTA1 and GSTP1 polymorphisms

Agnès Tran et al. Br J Clin Pharmacol. 2008 Feb.
No abstract available

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Figures

Figure 1
Figure 1
Cyclophosphamide metabolic pathways (adapted from Timm et al.[2]). The mutations (1) CYP2B6516TT, (2) CYP2C9*1/*3, (3) CYP3A5*3/*3, (4) GSTA1*A/*B, and (5) GSTP1*A/*B were identified in the presented case
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