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. 2007 Oct 11;9(21):4095-8.
doi: 10.1021/ol701533d. Epub 2007 Sep 18.

Synthesis of novel functionalized 3-spiropyrrolizidine and 3-spiropyrrolidine oxindoles from Baylis-Hillman adducts of isatin and heteroaldehydes with azomethine ylides via [3+2]-cycloaddition

Ponnusamy Shanmugam  1 , Baby Viswambharan, Suchithra Madhavan
Affiliations

Synthesis of novel functionalized 3-spiropyrrolizidine and 3-spiropyrrolidine oxindoles from Baylis-Hillman adducts of isatin and heteroaldehydes with azomethine ylides via [3+2]-cycloaddition

Ponnusamy Shanmugam et al. Org Lett. .

Abstract

A novel regioselective synthesis of a number of functionalized 3-spiropyrrolizidine and 3-spiropyrrolidine oxindoles from Baylis-Hillman adducts of isatin and heteroaldehydes via [3+2] cycloaddition of azomethine ylides in excellent yields has been reported.

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