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. 1991 Dec;11(6):375-9.
doi: 10.1016/s0934-8832(11)80191-5.

Completion of the last half of the structure of the human gene for the Pro alpha 1 (I) chain of type I procollagen (COL1A1)

A Westerhausen  1 , C D Constantinou, M Pack, M Z Peng, C Hanning, A S Olsen, D J Prockop
Affiliations

Completion of the last half of the structure of the human gene for the Pro alpha 1 (I) chain of type I procollagen (COL1A1)

A Westerhausen et al. Matrix. 1991 Dec.

Abstract

The nucleotide sequences of the 3'-half of the human gene for the pro alpha(I) chain of type I procollagen (COL1A1) is presented. The results provide the nucleotide sequences for 26 introns not previously analyzed. The sequences that are presented, together with those previously published, make it possible to design primers for the polymerase chain reaction for amplifying and sequencing the gene. The availability of such primers will greatly facilitate the current search for mutations that can cause common and rare diseases of connective tissue.

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