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. 2007 Oct 28;13(40):5367-70.
doi: 10.3748/wjg.v13.i40.5367.

Epidemiology of upper gastrointestinal cancers in Iran: a sub site analysis of 761 cases

Noushin Taghavi  1 , Dariush Nasrollahzadeh, Shahin Merat, Abbas Yazdanbod, Mahshid Hormazdi, Masoud Sotoudeh, Shahriar Semnani, Farhad Eslami, Haji-Amin Marjani, Saman Fahimi, Hooman Khademi, Reza Malekzadeh
Affiliations

Epidemiology of upper gastrointestinal cancers in Iran: a sub site analysis of 761 cases

Noushin Taghavi et al. World J Gastroenterol. .

Abstract

Aim: To define the sub site distribution of upper gastrointestinal cancers in three provinces of Iran.

Methods: The study was carried out in three provinces in Iran: Ardabil, Golestan, and Tehran. In Arbabil and Golestan, the data was collected from the sole referral center for gastrointestinal cancers and the local cancer registry. For Tehran province, data from two major private hospitals were used. All gastric and esophageal cancer patients diagnosed during the period from September 2000 and April 2002 were included in the study.

Results: A total of 761 patients with upper gastrointestinal cancers were identified, 314 from Ardabil, 261 from Golestan, and 186 from Tehran. In Tehran, the relative rate of cancer increased from the upper esophagus to the distal stomach. In Golestan, the reverse pattern was observed. In Ardabil, the mid portion (distal esophagus and proximal stomach) was involved most frequently.

Conclusion: There were considerable variations in the sub site of upper gastrointestinal cancers in the three provinces studied. We cannot provide any explanation for this variation. Further research aimed at explaining the discrepancies in sub site distribution of upper gastrointestinal cancers may help identify important risk factors.

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