Hypertension in connexin40-null mice: a renin disorder
- PMID: 17882239
- DOI: 10.1038/sj.ki.5002515
Hypertension in connexin40-null mice: a renin disorder
Abstract
Studies described in this issue indicate that the gap junction protein connexin40 (Cx40) appears to play an unexpected role in blood pressure regulation. In mice lacking this gap junction protein, renin secretion is high and not regulated by arteriolar pressure.
Comment on
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Connexin40 regulates renin production and blood pressure.Kidney Int. 2007 Oct;72(7):814-22. doi: 10.1038/sj.ki.5002423. Epub 2007 Jul 11. Kidney Int. 2007. PMID: 17622273
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