doi: 10.1016/j.diagmicrobio.2007.07.020.
Epub 2007 Sep 21.
False-positive Aspergillus antigen testing due to application of piperacillin/tazobactam--is it still an issue?
Affiliations
- PMID: 17889483
- DOI: 10.1016/j.diagmicrobio.2007.07.020
Item in Clipboard
False-positive Aspergillus antigen testing due to application of piperacillin/tazobactam--is it still an issue?
Diagn Microbiol Infect Dis.
2008 Jan.
Abstract
We evaluated the impact of piperacillin/tazobactam (PT) therapy on galactomannan enzyme immunoassay (GEI) testing (Platelia; Bio-Rad, Marnes La Coquette, France). Galactomannan contents of PT batches were highly variable. We found that false-positive GEI results can be avoided by performance of blood sampling before PT administration and by using separate sites for blood sampling and for administration of antibiotics.
Similar articles
-
False positivity of the Aspergillus galactomannan Platelia ELISA because of piperacillin/tazobactam treatment: does it represent a clinical problem?J Antimicrob Chemother. 2008 Nov;62(5):1109-12. doi: 10.1093/jac/dkn308. Epub 2008 Jul 21. J Antimicrob Chemother. 2008. PMID: 18647743
-
False positive test for aspergillus antigenemia related to concomitant administration of piperacillin and tazobactam.N Engl J Med. 2003 Dec 11;349(24):2366-7. doi: 10.1056/NEJM200312113492424. N Engl J Med. 2003. PMID: 14668472 No abstract available.
-
False positive galactomannan Platelia due to piperacillin-tazobactam.Med Mal Infect. 2012 Jan;42(1):10-4. doi: 10.1016/j.medmal.2011.10.018. Epub 2011 Dec 5. Med Mal Infect. 2012. PMID: 22153703
-
Diagnosis of invasive aspergillosis by galactomannan antigenemia detection using an enzyme immunoassay.Eur J Clin Microbiol Infect Dis. 2008 Apr;27(4):245-51. doi: 10.1007/s10096-007-0437-7. Epub 2008 Jan 9. Eur J Clin Microbiol Infect Dis. 2008. PMID: 18193305 Review.
-
Galactomannan antigen detection in the diagnosis of invasive aspergillosis.Expert Rev Mol Diagn. 2007 Jan;7(1):21-32. doi: 10.1586/14737159.7.1.21. Expert Rev Mol Diagn. 2007. PMID: 17187481 Review.
Cited by
-
The era of molecular and other non-culture-based methods in diagnosis of sepsis.Clin Microbiol Rev. 2010 Jan;23(1):235-51. doi: 10.1128/CMR.00043-09. Clin Microbiol Rev. 2010. PMID: 20065332 Free PMC article. Review.
-
Generic piperacillin/tazobactam is not associated with galactomannan false-positivity in adult patients with cancer: a case-control study.Eur J Clin Microbiol Infect Dis. 2015 Jul;34(7):1437-41. doi: 10.1007/s10096-015-2370-5. Epub 2015 Apr 17. Eur J Clin Microbiol Infect Dis. 2015. PMID: 25894983
-
The interaction between piperacillin/tazobactam and assays for Aspergillus galactomannan and 1,3-beta-D-glucan in patients without risk factors for invasive fungal infections.Infection. 2010 Jun;38(3):217-21. doi: 10.1007/s15010-010-0003-6. Epub 2010 Mar 17. Infection. 2010. PMID: 20237947
-
The interaction between piperacillin-tazobactam and Aspergillus galactomannan antigenemia assay: is the story over?Infection. 2013 Feb;41(1):293-4. doi: 10.1007/s15010-012-0327-5. Epub 2012 Sep 7. Infection. 2013. PMID: 22956475 No abstract available.
-
Drug-laboratory interaction between beta-lactam antibiotics and the galactomannan antigen test used to detect mould infections.Braz J Infect Dis. 2014 Sep-Oct;18(5):544-7. doi: 10.1016/j.bjid.2014.03.009. Epub 2014 May 13. Braz J Infect Dis. 2014. PMID: 24833197 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
