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Comment
. 2007 Sep 21;130(6):981-3.
doi: 10.1016/j.cell.2007.09.004.

DISC1 puts the brakes on neurogenesis

Alex Dranovsky  1 , Rene Hen
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Comment

DISC1 puts the brakes on neurogenesis

Alex Dranovsky et al. Cell. .
Free article

Abstract

The gene DISC1 (Disrupted-in-Schizophrenia 1) is a leading candidate gene for schizophrenia. In this issue, Duan et al. (2007) present evidence implicating DISC1 in the maturation and integration of newly generated neurons in the adult mouse hippocampus. Surprisingly, DISC1 appears to have opposite effects on neurogenesis during development and in adulthood.

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