Acceleration of transformation of rat embryo cells by rat type C virus
- PMID: 178908
- PMCID: PMC515606
- DOI: 10.1128/JVI.18.2.776-782.1976
Acceleration of transformation of rat embryo cells by rat type C virus
Abstract
Sprague-Dawley and Fischer rat embryo cells became spontaneously transformed about 20 passages after release of endogenous ecotropic type C virus (SD-RaLV and F-RaLV). The virus-producing transformed cells showed loss of contact inhibition, increased growth rate, and tumorigenicity in vivo. Exogenous infection of other Fischer rat embryo cultures in early passage with SD-RaLV and F-RaLV markedly accelerated their rates of transformation.
Similar articles
-
Spontaneous release of endogenous ecotropic type C virus from rat embryo cultures.J Virol. 1976 May;18(2):799-803. doi: 10.1128/JVI.18.2.799-803.1976. J Virol. 1976. PMID: 58077 Free PMC article.
-
Inhibition of spontaneous transformation of rat embryo cells releasing endogenous type C virus by virus-specific antiserum.J Natl Cancer Inst. 1979 Sep;63(3):745-50. doi: 10.1093/jnci/63.3.745. J Natl Cancer Inst. 1979. PMID: 89211
-
Consecutive activation of a type C RNA and polyoma virus from tumors induced by polyoma virus-transformed rat cells.Proc Soc Exp Biol Med. 1974 Dec;147(3):730-5. doi: 10.3181/00379727-147-38427. Proc Soc Exp Biol Med. 1974. PMID: 4141098 No abstract available.
-
[Recent data on the development of virus-induced tumors].Dtsch Med Wochenschr. 1969 Jan 31;94(5):232-6. doi: 10.1055/s-0028-1108935. Dtsch Med Wochenschr. 1969. PMID: 4303141 Review. German. No abstract available.
-
Introduction to virus-caused cancer: type C virus.Cancer. 1974 Oct;34(4 Suppl):suppl:1363-7. doi: 10.1002/1097-0142(197410)34:8+<1363::aid-cncr2820340805>3.0.co;2-p. Cancer. 1974. PMID: 4371356 Review. No abstract available.
Cited by
-
Spontaneous release of endogenous ecotropic type C virus from rat embryo cultures.J Virol. 1976 May;18(2):799-803. doi: 10.1128/JVI.18.2.799-803.1976. J Virol. 1976. PMID: 58077 Free PMC article.
-
Transformed phenotypes in long-term cultures persistently infected with bovine leukemia virus.Can J Comp Med. 1981 Apr;45(2):154-8. Can J Comp Med. 1981. PMID: 6266621 Free PMC article.
-
In vitro isolation of stable rat sarcoma viruses.Proc Natl Acad Sci U S A. 1978 Jun;75(6):2972-6. doi: 10.1073/pnas.75.6.2972. Proc Natl Acad Sci U S A. 1978. PMID: 208081 Free PMC article.
-
Genetic analysis of the rat leukemia virus: influence of viral sequences in transduction of the c-ras proto-oncogene and expression of its transforming activity.J Virol. 1998 Dec;72(12):9906-17. doi: 10.1128/JVI.72.12.9906-9917.1998. J Virol. 1998. PMID: 9811727 Free PMC article.
-
Prevention of 3-methylcholanthrene-induced fibrosarcomas in rats pre-inoculated with endogenous rat retrovirus.Proc Natl Acad Sci U S A. 1981 Apr;78(4):2526-7. doi: 10.1073/pnas.78.4.2526. Proc Natl Acad Sci U S A. 1981. PMID: 6941305 Free PMC article.
References
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources