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Case Reports
. 1991:309A:369-72.
doi: 10.1007/978-1-4899-2638-8_84.

A xanthinuric family--the proposita having immunologically reactive xanthine oxidase but no xanthine oxidase activity

T Yamamoto  1 , Y Moriwaki, S Takahashi, T Hada, M Suda, H Imanishi, O E Agbedana, M Nanahoshi, K Higashino
Affiliations
Case Reports

A xanthinuric family--the proposita having immunologically reactive xanthine oxidase but no xanthine oxidase activity

T Yamamoto et al. Adv Exp Med Biol. 1991.

Abstract

The antibody was raised against purified human liver xanthine oxidase in a rabbit. In a xanthinuric patient, the double immunodiffusion method demonstrated the existence of an immunologically reactive duodenal mucosa xanthine oxidase which did not possess xanthine oxidase activity. These results indicated that xanthine oxidase protein is abnormal in structure and/or amino acid sequence.

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