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Review
. 2007 Sep;27(3):417-9.
doi: 10.1016/j.immuni.2007.08.008.

Foxp3+ regulatory T cells: selfishness under scrutiny

Geoffrey L Stephens  1 , Ethan M Shevach
Affiliations
Free article
Review

Foxp3+ regulatory T cells: selfishness under scrutiny

Geoffrey L Stephens et al. Immunity. 2007 Sep.
Free article

Abstract

The Foxp3+ T cell lineage is thought to arise from self-specific precursors during development. By using a unique mouse model, Pacholczyk et al. (2007) present compelling evidence that self-specific cells are exceedingly rare among Foxp3(-) and, surprisingly, Foxp3+ subsets.

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