Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2007;46(43):8250-3.
doi: 10.1002/anie.200703276.

Complex alpha-pyrones synthesized by a gold-catalyzed coupling reaction

Tuoping Luo  1 , Stuart L Schreiber
Affiliations

Complex alpha-pyrones synthesized by a gold-catalyzed coupling reaction

Tuoping Luo et al. Angew Chem Int Ed Engl. 2007.
No abstract available

PubMed Disclaimer

Figures

Figure 1
Figure 1
Syntheses of trisubstituted α-pyrones via transition metal-catalyzed cascade reactions.
Figure 2
Figure 2
Racemic products result from non-racemic propargyl propiolates.
Figure 3
Figure 3
Cascade process yielding a tricyclic α-pyrone.
Figure 4
Figure 4
Intramolecular functional group-pairing reaction involving substituents attached to distinct building blocks prior to the intermolecular coupling reaction (c.f., “Build/Couple/Pair strategy”[2]).
See this image and copyright information in PMC

References

    1. For examples, see: Kumagai N, Muncipinto G, Schreiber SL. Angew Chem. 2006;118:3717–3720.Angew Chem Int Ed. 2006;45:3635–3638.Spiegel DA, Schroeder FC, Duvall JR, Schreiber SL. J Am Chem Soc. 2006;128:14766–14767.

    1. Nielsen TE, Schreiber SL. submitted.
    1. Dickinson JM. Nat Prod Rep. 1993;10:71–98. - PubMed
    2. Steyn PS, van Heerden FR. Nat Prod Rep. 1998;15:397–413. - PubMed
    3. McGlacken GP, Fairlamb IJ. Nat Prod Rep. 2005;22:369–385. - PubMed
    4. Salomon CE, Magarvey NA, Sherman DH. Nat Prod Rep. 2004;21:105–121. - PubMed
    5. van Raaij MJ, Abrahams JP, Leslie AG, Walker JE. Proc Natl Acad Sci U S A. 1996;93:6913–6917. - PMC - PubMed
    6. Wu PL, Hsu YL, Wu TS, Bastow KF, Lee KH. Org Lett. 2006;8:5207–5210. - PubMed
    7. Clark BR, Capon RJ, Lacey E, Tennant S, Gill JH. Org Lett. 2006;8:701–704. - PubMed
    8. Lee JC, Lobkovsky E, Pliam NB, Strobel G, Clardy J. J Org Chem. 1995;60:7076–7077.
    9. Thaisrivongs S, Janakiraman MN, Chong KT, Tomich PK, Dolak LA, Turner SR, Strohbach JW, Lynn JC, Horng MM, Hinshaw RR, Watenpaugh KD. J Med Chem. 1996;39:2400–2410. - PubMed
    1. Burke MD, Schreiber SL. Angew Chem. 2004;116:48–60. - PubMed
    2. Angew Chem Int Ed. 2004;43:46–58. - PubMed
    1. Jung ME, Hagenah JA. J Org Chem. 1987;52:1889–1902.
    2. Dieter RK, Fishpaugh JR. J Org Chem. 1988;53:2031–2046.
    3. Douglas CJ, Sklenicka HM, Shen HC, Mathias DS, Degen SJ, Golding GM, Morgan CD, Shih RA, Mueller KL, Scurer LM, Johnson EW, Hsung RP. Tetrahedron. 1999;55:13683–13696.
    4. Ma S, Yu S, Yin S. J Org Chem. 2003;68:8996–9002. - PubMed
    5. Hachiya I, Shibuya H, Shimizu M. Tetrahedron Lett. 2003;44:2061–2063.
    6. Gilbreath SG, Harris CM, Harris TM. J Am Chem Soc. 1988;110:6172–6179. - PubMed

Publication types

LinkOut - more resources