[Amiodarone associated optic neuropathies--two cases reports]

Abstract

We described two cases with papilledema within the first months of amiodarone treatment. The particular aspects of these cases are, on one hand the development of the optic neuropathy before any toxic change of the cornea and on the other hand the daily and weekly doses prescribed in both cases. We reviewed the meta-analysis studies on the subject and the different pathogenic mechanisms described until now.