Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2007 Nov-Dec;18(6):1749-55.
doi: 10.1021/bc060387g. Epub 2007 Sep 26.

Wheat germ agglutinin-modified trifunctional nanospheres for cell recognition

Hai-Yan Xie  1 , Min Xie, Zhi-Ling Zhang, Yan-Min Long, Xin Liu, Ming-Liang Tang, Dai-Wen Pang, Zheng Tan, Calum Dickinson, Wuzong Zhou
Affiliations

Wheat germ agglutinin-modified trifunctional nanospheres for cell recognition

Hai-Yan Xie et al. Bioconjug Chem. 2007 Nov-Dec.

Abstract

A simple and convenient strategy has been put forward to fabricate smart fluorescent magnetic wheat germ agglutinin-modified trifunctional nanospheres (WGA-TFNS) for recognition of human prostate carcinoma DU-145 cells which are surface-expressed with sialic acid and N-acetylglucosamine. These TFNS can be easily manipulated, tracked, and conveniently used to capture and separate target cells. The presence of wheat germ agglutinin on the surface of WGA-TFNS was confirmed by FTIR, biorecognition of carboxymethyl chitin-modified quantum dots (CM-CT-QDs), and bacterium Staphylococcus aureus. The success in recognizing DU-145 cells by the WGA-TFNS indicates that WGA-TFNS could be applicable.

PubMed Disclaimer

Publication types

Substances

LinkOut - more resources